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Lecture 11

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Final Exam

Go to References and Resources for Biological Safety

Lecture 11

Animal Biosafety

BSP&P: Ch 12, 28
BMBL 5th Edition: Sec. IV, VI, & App. D
RDNA: App. Q

By the end of the class, students will be able to:

  • Provide an overview of the range of hazards unique to animal facilities for small or conventional research animals
  • Review the signs and symptoms of laboratory animal allergy and outline the basic control methods to reduce or eliminate its occurrence
  • Discuss the concept of risk assessment as it pertains to experiments involving research animals
  • Review the biohazard containment and control mechanisms required for the safe housing and handling of naturally or experimentally infected research animals
  • Outline administrative controls that may be utilized to control biohazards in animal research
  • Give an overview of the regulatory and resource groups applicable to experiments involving laboratory animals used in research

Lecture 11

Lecture 11a: Risk Assessment in Animal Biosafety

Lecture 11b: CDC/NIH Vertebrate Animal Biosafety Level Criteria


If possible, make arrangements in advance with your institution’s Animal Care and Use Committee or Animal Resource Center representatives and schedule a visit to an active animal housing facility to get an opportunity to see the entry and exit stations, the animal room doors and required signage, a glimpse at the various containment and control equipment located within each room, the personal protective equipment utilized, the numerous support areas for supplies, the sanitation rooms, and associated storage locations.  Although the tour does not have to include direct entry into animal rooms, all students must be cleared for entry by the host institution and escorted at all times during the tour within the facility.


  1. Working Safely with Laboratory Animals:  Animal Biosafety Levels 1 – 3 (ABSL1 & 2)
  2. (Available from the Elizabeth R. Griffin Research Foundation)

It is helpful to recruit representatives from the institution’s Animal Care and Use Committee or the Animal Resources Center to provide a brief overview of an Animal Care and Use Program to the students.  This presentation can also discuss the relationship between the Animal Care and Use Program and the Environmental Health and Safety Program to ensure that hazards associated with research animals are addressed.



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