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RiskGroupDb

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Items 1815

Agent Type Genus / Virus Group Species / Virus Name NIH NIH notes BMBL Australia / New Zealand Austrailia / New Zealand notes Belgium Belgium notes Canada Canada PSDS Canada Notes European Community European Community notes Georgia Georgia notes Germany Germany notes Singapore Singapore notes Singapore schedule Switzerland Switzerland notes United Kingdom United Kingdom notes Human Pathogen Animal Pathogen Plant Pathogen Select Agent CDC Select Agent USDA
bacteria Clostridium spp. 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/clostridium.html This risk group applies to the�Clostridium�genus as a whole, and may not apply to every species within the genus. 2 2 2 Yes Yes No No No
virus Reoviridae Colorado tick fever virus 2 2 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/colorado-tick-fever-virus.html 2 2 2 PHV 2 Yes Yes No No No
bacteria Corynebacterium diphtheriae 2 2 2 2 T 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/corynebacterium-diphtheriae.html 2 T, V 2 2 T, V 2 2 T,V Yes No No No No
bacteria Coxiella burnetii 3 Except the Phase II, Nine Mile strain listed in Appendix B-II-A, Risk Group 2 (RG2) - Bacterial Agents Including Chlamydia 3 3 Australia (cultures, animal work and concentrates) (Special precautions: V, P); 3 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/coxiella-burnetii.html 3 3* 3 Z 3 First Schedule Part II 3 3 Yes Yes No Yes No
virus Picornaviridae Acute haemorrhagic conjunctivitis virus (AHC) https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/coxsackievirus-pathogen-safety-data-sheet.html 2 2 2 2 Synonyms: Coxsackievirus CA24 (A24); Enterovirus 70 No No No No No
virus Picornaviridae Coxsackie virus 2 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/coxsackievirus-pathogen-safety-data-sheet.html 2 2 2 2 PH 2 Yes Yes No No No
virus Prion Creutzfeldt-Jacob disease 3 2 2 3 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/creutzfeldt-jakob-agent-kuru-agent.html Biosafety level 3 facilities, practices and containment equipment for activities involving these agents; also listed under biosafety level 2 with special precautions; level of containment will depend on the nature of the manipulations and the amount of sera, bio/necropsy materials handled 3 **, D, d 3* 3(**) 3 First schedule part 1 3 ** PH TSE 3 * Yes No No No No
virus Prion Kuru 3 2 2 3 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/creutzfeldt-jakob-agent-kuru-agent.html Biosafety level 3 facilities, practices and containment equipment for activities involving these agents; also listed under biosafety level 2 with special precautions; level of containment will depend on the nature of the manipulations and the amount of sera, bio/necropsy materials handled 3 **, D, d 3* 3(**) 3 First schedule part 1 3 ** PH TSE 3 * Yes No No No No
virus Prion Kuru & Creutzfeldt-Jacob agents 2 2 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/creutzfeldt-jakob-agent-kuru-agent.html Biosafety level 3 facilities, practices and containment equipment for activities involving these agents; also listed under biosafety level 2 with special precautions; level of containment will depend on the nature of the manipulations and the amount of sera, bio/necropsy materials handled 3 (**), D, d 3* 3(**) 3 First schedule part 1 3 **, PH, TSE 3 Yes No No No No
virus Prion Scrapie 2 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/creutzfeldt-jakob-agent-kuru-agent.html Biosafety level 3 facilities, practices and containment equipment for activities involving these agents; also listed under biosafety level 2 with special precautions; level of containment will depend on the nature of the manipulations and the amount of sera, bio/necropsy materials handled 3* 2 2 2 No Yes No No No
virus Prion Variant Creutzfeldt-Jacob disease 2 3 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/creutzfeldt-jakob-agent-kuru-agent.html Biosafety level 3 facilities, practices and containment equipment for activities involving these agents; also listed under biosafety level 2 with special precautions; level of containment will depend on the nature of the manipulations and the amount of sera, bio/necropsy materials handled 3 (**), D, d 3* 3(**) 3 First schedule part 1 3 Yes No No No No
virus Bunyaviridae Crimean-Congo haemorrhagic fever 4 4 4 4 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/crimean-congo-haemorrhagic-fever-virus.html 4 4* 4 4 Second schedule 4 PHV 4 Yes Yes No Yes No
parasite Cryptosporidium parvum 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/cryptosporidium-parvum-pathogen-safety-data-sheet.html 2 2 2 Z 2 AAH, AHH, ZOP 2 Yes Yes No No No
parasite Cyclospora cayetanensis 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/cyclospora-pathogen-safety-data-sheet.html 2 2 2 Z 2 AHH 2 Yes No No No No
parasite Cyclospora spp https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/cyclospora-pathogen-safety-data-sheet.html 2 2 AAH, AHH 2 Yes Yes No No No
virus Herpesviridae Cytomegalovirus (CMV) 2 2 2 Respiratory protection should be considered 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/cytomegalovirus.html 2 2 2 PH 2 Yes No No No No
virus Flaviviridae Dengue virus 2 Serotypes 1, 2, 3, and 4 2 2 Dengue 1, 2, 3 and 4 3 Type 1-4 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/dengue-fever-virus-1-2-3-4-pathogen-safety-data-sheet.html 3 type 1-4 3 3 3 PHV 3 (Types 1-4) Yes No No No No
virus Togaviridae Eastern equine encephalitis virus 3 3 3 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/eastern-equine-encephalitis.html 3 V 3 3 3 First schedule part 2 3 PHV 3 Classified under SAPO Yes Yes No Yes No
virus Togaviridae Western equine encephalitis virus 3 3 3 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/eastern-equine-encephalitis.html 3 V 3 3 3 First schedule part 1 3 PHV 3 Yes Yes No No No
virus Filoviridae Ebola virus 4 4 4 4 4 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/ebolavirus.html 4 4 4 4 Second Schedule 4 PHV 4 Yes Yes No Yes No
parasite Echinococcus granulosus 2 2 2 See Echinococcus spp. 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/echinococcus-granulosus-pathogen-safety-data-sheet.html 3 (**) 3* 3(**) Z 2, 3 **, AAH, AHH, PIH, ZOP, OST 3 Classified under SAPO Yes Yes No No No
parasite Echinococcus multilocularis 2 2 2 See Echinococcus spp. 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/echinococcus-multilocularis.html 3 (**) 3* 3(**) Z 2, 3 **, AAH, AHH, OST, PIH, ZOP 3 Classified under SAPO Yes Yes No No No
virus Picornaviridae Echo virus 2 All types 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/echovirus-pathogen-safety-data-sheet.html 2 2 2 Yes No No No No
virus Picornaviridae Echoviruses 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/echovirus-pathogen-safety-data-sheet.html 2 2 2 PH 2 Yes No No No No
bacteria Edwardsiella tarda 2 2 2 RG 3 in animals https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/edwardsiella-tarda.html 2 2 2 ht 2 2 Yes Yes No No No
parasite Entamoeba histolytica 2 2 2 G 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/entamoeba-histolytica-pathogen-safety-data-sheet.html 2 2 2 Z 2 AAH, AHH, ZOP 2 Yes Yes No No No
bacteria Enterobacter spp. https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/enterobacter.html This risk group applies to the genus as a whole, and may not apply to every species within the genus. 2 2 2 Yes No No No No
bacteria Enterococcus faecium 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/enterococcus-faecalis.html 2 TA 2 TA (Streptococcus faecium) Yes No No No No
virus Picornaviridae Enterovirus 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/enterovirus-70.html Enterovirus 70 2 V 2 2 PM, PH Yes No No No No
fungus Epidermophyton floccosum 2 2 2 (mitosporic Arthrodermataceae); both human and animal risk group 2 pathogen 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/epidermophyton-floccosum-microsporum-trichophyton.html 2 A 2 2 A 2 h, Acrothecium floccosum, E. clypeiforme, E. inguinale, E. plicarum, Trichophyton cruris, Trichophyton floccosum, Trichophyton inguinale, Trichophyton intertriginis, Trichothecium floccosum, obsolete synonym 2 A Yes Yes No No No
virus Herpesviridae Epstein-Barr virus (EBV) 2 2 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/epstein-barr-virus.html 2 2 2 2 PH 2 Yes No No No No
bacteria Escherichia coli 2 All enteropathogenic, enterotoxigenic, enteroinvasive and strains bearing K1 antigen, including E. coli O157:H7 2 2 Australia (Pathogenic E. coli; except Vero cytotoxin-producing (VTEC) strains and genetically crippled strains) 2 (cytoxic strains are RG 3 incl. O157:H7); T(*) 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/escherichia-coli-enterohemorrhagic.html 2 (**) verocytoxigenic strains O157:H7 or O103, RG3 2 3 (enterohaemorraghic strains, e.g., 157:H7, O13), others RG-2, * 2 IMP ((enterohemorrhagic (EHEC) strains such as O157:H7 or O103 are RG 3! **, EHEC) 2 (with the exception of non-pathogenic strains) (verocytotoxigenic strains are RG 3, eg O157:H7 or O103), T Yes Yes No No No
parasite Fasciola gigantica 2 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/fasciola-hepatica.html Fasciola hepatica 2 2 2 Z 2 AAH, AHH, ZOP 2 Yes No No No No
parasite Fasciola hepatica 2 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/fasciola-hepatica.html 2 2 2 Z 2 AAH, AHH, ZOP 2 Yes Yes No No No
bacteria Francisella tularensis (Type A) 3 Except those strains listed in Appendix B-II-A, Risk Group 2 (RG2) - Bacterial Agents Including Chlamydia 3 3 3 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/francisella-tularensis-material-safety-data-sheets-msds.html 3 3* 2 Z, (subsp. holarctica, mediasiatica) 3 Except for attenduated strains UTAH 112, live vaccine strain and B38 First Schedule Part II 3 (subsp. Holarctica, mediasiatica, tularensis) 3 Yes Yes No Yes No
bacteria Francisella tularensis (Type B) 2 Specifically *F. tularensis subspecies novicida [aka F. novicida], strain Utah 112; *F. tularensis subspecies holarctica LVS; *F. tularensis biovar tularensis strain ATCC 6223 (aka strain B38). *For research involving high concentrations, BL3 practices should be considered. 3 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/francisella-tularensis-material-safety-data-sheets-msds.html 2 2 3 Z, (subsp. tularensis) 3 Except for attenduated strains UTAH 112, live vaccine strain and B38 First Schedule Part II 2 Yes Yes No Yes No
bacteria Fusobacterium spp. 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/fusobacterium.html This risk group applies to the genus as a whole, but does not necessarily reflect the risk group classification of every species within the genus. 2 2 Yes No No No No
bacteria Gemella haemolysans https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/gemella.html 2 2 Yes No No No No
parasite Giardia duodenalis 2 2 2 2 Syn. Giardia lamblia, Giardia intestinalis https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/giardia-lamblia.html Giardia lamblia 2 2 Z 2 Giardia lamblia, AAH, AHH, ZOP Yes Yes No No No
parasite Giardia intestinalis 2 2 2 Syn. Giardia lamblia, Giardia intestinalis 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/giardia-lamblia.html Giardia lamblia 2 2 Z 2 Giardia lamblia, AAH, AHH, ZOP 2 Yes Yes No No No
parasite Giardia lamblia 2 2 Also known as Giardia duodenalis and Giardia intestinalis 2 syn. Giardia intestinalis, G. duodenalis https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/giardia-lamblia.html 2 Giardia intestinalis 2 2 Z 2 AAH, AHH, ZOP 2 (Giardia intestinalis) Yes Yes No No No
bacteria Haemophilus ducreyi 2 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/haemophilus-ducreyi.html 2 2 2 2 2 Yes No No No No
bacteria Haemophilus influenzae 2 2 2 2 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/haemophilus-influenzae.html 2 2 2 V 2 2 Yes No No No No
virus Bunyaviridae Belgrade (see Dobrava) 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/hantavirus.html Hantavirus spp. 3 also known as Dobrava 3 3 PHV 3 No No No No No
virus Bunyaviridae Dobrava/Belgrade virus (DOBV) 3 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/hantavirus.html Hantavirus spp. 3 3 3 3 PHV 3 Yes No No No No
virus Bunyaviridae Hanta virus 3 3 3 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/hantavirus.html Hantavirus spp. 2 other, unless listed; Seoul and Hantaan RG 3 3 First schedule part 1 3 PHV; Prospect Hill virus and Thottapalayam virus are 2 3 Prospect Hill and Puumala (2) Yes No No No No
virus Bunyaviridae Hantaan (Korean haemorrhagic fever) 3 3 3 A (and related viruses) Animal inoculation to be performed under PC4 containment 3 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/hantavirus.html Hantavirus spp. 3 3 3 3 PHV 3 Yes Yes No No No
virus Bunyaviridae other hantaviruses 3 Animal inoculations to be performed under PC4 containment https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/hantavirus.html Hantavirus spp. 2 Yes Yes No No No
virus Bunyaviridae Puumala virus 3 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/hantavirus.html Hantavirus spp. 2 2 2 3 2 Yes No No No No
virus Bunyaviridae Seoul virus 3 3 https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/hantavirus.html Hantavirus spp. 3 3 3 3 First schedule part 1 3 PHV 3 Yes No No No No