Agent Type |
Genus / Virus Group |
Species / Virus Name |
NIH |
NIH notes |
BMBL |
Australia / New Zealand |
Austrailia / New Zealand notes |
Belgium |
Belgium notes |
Canada |
Canada PSDS |
Canada Notes |
European Community |
European Community notes |
Georgia |
Georgia notes |
Germany |
Germany notes |
Singapore |
Singapore notes |
Singapore schedule |
Switzerland |
Switzerland notes |
United Kingdom |
United Kingdom notes |
Human Pathogen |
Animal Pathogen |
Plant Pathogen |
Select Agent CDC |
Select Agent USDA |
virus
|
Bunyaviridae
|
Other bunyaviridae known to be pathogenic
|
|
|
|
|
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
|
|
2
|
|
Yes
|
Yes
|
No
|
No
|
No
|
bacteria
|
Clostridium
|
perfringens
|
|
|
|
|
|
2
|
|
2
|
https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/clostridium-perfringens.html
|
This risk group applies to the species as a whole, and may not apply to every strain.
|
2
|
|
2
|
|
2
|
ht, T
|
|
|
|
2
|
|
2
|
|
Yes
|
Yes
|
No
|
No
|
No
|
virus
|
Arenaviridae
|
Amapari virus
|
|
|
2
|
|
|
2
|
|
|
|
|
|
|
2
|
|
2
|
|
|
|
|
2
|
|
2
|
|
Yes
|
No
|
No
|
No
|
No
|
bacteria
|
Rickettsia
|
montanensis
|
|
|
2
|
|
|
3
|
: (*)
|
|
|
|
3
|
**
|
3*
|
formerly Rickettsia canadensis
|
2
|
Z
|
3
|
Rickettsia - all species
|
First Schedule Part II
|
3
|
PV?**
|
3
|
|
Yes
|
Yes
|
No
|
No
|
No
|
parasite
|
Echinococcus
|
granulosus
|
2
|
|
2
|
2
|
See Echinococcus spp.
|
3
|
|
|
https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/echinococcus-granulosus-pathogen-safety-data-sheet.html
|
|
3
|
(**)
|
3*
|
|
3(**)
|
Z
|
|
|
|
2, 3
|
**, AAH, AHH, PIH, ZOP, OST
|
3
|
Classified under SAPO
|
Yes
|
Yes
|
No
|
No
|
No
|
virus
|
Parvoviridae
|
Hamster H-1 virus
|
|
|
|
|
|
2
|
H-1 parvovirus
|
|
|
|
|
|
|
|
1
|
t2
|
|
|
|
|
|
|
|
No
|
Yes
|
No
|
No
|
No
|
virus
|
Hepadnaviridae
|
Ground squirrel hepatitis B virus
|
|
|
|
|
|
3
|
|
|
|
|
|
|
|
|
1
|
t2
|
|
|
|
2
|
PM
|
|
|
No
|
Yes
|
No
|
No
|
No
|
bacteria
|
Citrobacter
|
sedlakii
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
2
|
|
|
|
|
2
|
|
|
|
Yes
|
No
|
No
|
No
|
No
|
bacteria
|
Brucella
|
abortus
|
3
|
|
3
|
3
|
|
3
|
|
3
|
https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/brucella-b-abortus-b-canis-b-melitensis-b-suis-material-safety-data-sheets-msds.html
|
iosafety level 2 practices for activities involving clinical materials of human or animal origin; Biosafety level 3 containment, practices and facilities for all manipulations of cultures and for experimental animal studies.
|
3
|
|
3*
|
|
3
|
Z
|
3
|
Except for the attenduate strains 19 or RB51
|
First Schedule Part II
|
|
|
3
|
|
Yes
|
Yes
|
No
|
Yes
|
Yes
|
parasite
|
Ternidens
|
deminutus
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
2
|
Z
|
|
|
|
2
|
AAH AHH ZOP
|
|
|
Yes
|
No
|
No
|
No
|
No
|
bacteria
|
Hallella
|
seregens
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
|
|
|
|
|
2
|
|
|
|
Yes
|
No
|
No
|
No
|
No
|
virus
|
Papovaviridae
|
Rabbit (RK virus)
|
|
|
|
|
|
2
|
Rabbit kidney vacuolating virus
|
|
|
|
|
|
|
|
1
|
t2
|
|
|
|
|
|
|
|
No
|
Yes
|
No
|
No
|
No
|
virus
|
Flaviviridae
|
Hepatitis G virus
|
|
|
|
|
|
3
|
|
|
|
|
3
|
(**), D
|
|
|
1
|
|
|
|
|
3
|
**, PH
|
3
|
|
Yes
|
No
|
No
|
No
|
No
|
bacteria
|
Dermatiphulus
|
chelonae
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
|
|
|
|
|
2
|
PV
|
|
|
No
|
Yes
|
No
|
No
|
No
|
bacteria
|
Pasteurella
|
gallinarum
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
2
|
PV
|
|
|
No
|
Yes
|
No
|
No
|
No
|
bacteria
|
Treponema
|
amylovorum
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
2
|
|
|
|
|
2
|
|
|
|
Yes
|
No
|
No
|
No
|
No
|
virus
|
Togaviridae
|
Alphaviruses
|
|
|
|
3
|
|
2
|
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
2
|
|
Yes
|
Yes
|
No
|
No
|
No
|
bacteria
|
Catonella
|
morbi
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
2
|
|
|
|
|
2
|
|
|
|
Yes
|
No
|
No
|
No
|
No
|
bacteria
|
Borrelia
|
dugesii
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
2
|
t
|
|
|
|
2
|
PV
|
|
|
No
|
Yes
|
No
|
No
|
No
|
bacteria
|
Actinomyces
|
spp.
|
|
|
|
2
|
|
|
species which are known to be pathogens in humans
|
|
https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/actinomyces-pathogen-safety-data-sheet.html
|
|
2
|
|
2
|
|
|
|
|
|
|
|
|
2
|
|
No
|
No
|
No
|
No
|
No
|
bacteria
|
Moraxella
|
atlantae
|
2
|
|
|
|
|
2
|
|
|
https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/moraxella.html
|
|
|
|
|
|
2
|
|
|
|
|
2
|
|
|
|
Yes
|
No
|
No
|
No
|
No
|
virus
|
Poxviridae
|
other pathogenic orthopoxviruses not in RG 2 or 4
|
2
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
No
|
No
|
No
|
No
|
No
|
bacteria
|
Gemella
|
palaticanis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1
|
|
|
|
|
2
|
|
|
|
Yes
|
No
|
No
|
No
|
No
|
virus
|
Iridoviridae
|
Iridoviruses of chilids, perch, goldfish, common cod, carp and cat-fish
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
No
|
Yes
|
No
|
No
|
No
|
bacteria
|
Faenia
|
rectivirgula
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1
|
PIIC (see Saccharopolyspora rectivirgula)
|
|
|
Yes
|
Yes
|
No
|
No
|
No
|
parasite
|
Clonorchis
|
sinensis
|
|
|
|
2
|
|
2
|
|
|
https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/clonorchis-sinensis-pathogen-safety-data-sheet.html
|
|
2
|
|
|
|
2
|
Z
|
|
|
|
2
|
AAH, AHH, ZOP
|
2
|
Opisthorchis sinensis
|
Yes
|
Yes
|
No
|
No
|
No
|
bacteria
|
Corynebacterium
|
cystitidis
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
2
|
t
|
|
|
|
2
|
PV
|
|
|
No
|
Yes
|
No
|
No
|
No
|
bacteria
|
Neisseria
|
meningitidis
|
2
|
|
2
|
2
|
b: Low infectious dose, high pathogenicity, common source of laboratory-acquired infections.; f: High risk of aerosol spread.
|
2
|
|
2
|
https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/neisseria-meningitidis.html
|
|
2
|
V
|
2
|
|
2
|
V
|
|
|
|
2
|
|
2
|
Vaccine available
|
Yes
|
No
|
No
|
No
|
No
|
bacteria
|
Streptococcus
|
constellatus
|
2
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
2
|
|
|
|
|
2
|
|
|
|
Yes
|
No
|
No
|
No
|
No
|
bacteria
|
Bartonella
|
henselae
|
2
|
|
|
2
|
|
2
|
|
|
https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/bartonella-henselae.html
|
|
|
|
|
|
2
|
Z
|
|
|
|
2
|
|
|
|
Yes
|
No
|
No
|
No
|
No
|
bacteria
|
Mycoplasma
|
equirhinis
|
2
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
2
|
t
|
|
|
|
2
|
PV
|
|
|
No
|
Yes
|
No
|
No
|
No
|
virus
|
Retroviridae
|
Simian sarcoma viruses (SSV)
|
|
|
|
|
|
3
|
|
|
|
|
|
|
|
|
|
|
|
|
|
2
|
PM
|
|
|
No
|
Yes
|
No
|
No
|
No
|
bacteria
|
Acinetobacter
|
spp.
|
2
|
|
|
2
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
No
|
No
|
No
|
No
|
No
|
bacteria
|
Legionella
|
spp.
|
2
|
|
|
2
|
|
|
|
|
|
|
2
|
|
2
|
|
|
|
2
|
All species and all Legionella-like organisms
|
Third schedule
|
|
|
2
|
See also Fluoribacter bozemanae
|
Yes
|
No
|
No
|
No
|
No
|
virus
|
Picornaviridae
|
Murine poliovirus (Theiler's encephalomyelitis virus, TO, FA, GD7)
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
No
|
Yes
|
No
|
No
|
No
|
bacteria
|
Erysipelothrix
|
rhusiopathiae
|
2
|
|
|
2
|
|
2
|
|
|
|
|
2
|
|
2
|
|
2
|
Z
|
|
|
|
2
|
PV
|
2
|
|
Yes
|
Yes
|
No
|
No
|
No
|
bacteria
|
Prevotella
|
nigrescens
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
2
|
|
|
|
|
2
|
|
|
|
Yes
|
No
|
No
|
No
|
No
|
bacteria
|
Yersinia
|
pseudotuberculosis
|
|
|
|
|
|
2
|
|
2
|
https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/yersinia-pseudotuberculosis.html
|
|
2
|
|
2
|
|
2
|
Z
|
|
|
|
2
|
(Yersinia pseudotuberculosis subsp. pestis RG 3?)
|
2
|
|
Yes
|
Yes
|
No
|
No
|
No
|
bacteria
|
Mycoplasma
|
imitans
|
2
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
2
|
t
|
|
|
|
2
|
PV
|
|
|
No
|
Yes
|
No
|
No
|
No
|
bacteria
|
Sphaerophorus
|
necrophorus
|
2
|
|
|
2
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Yes
|
No
|
No
|
No
|
No
|
bacteria
|
Bacillus
|
anthracis
|
2
|
|
2
|
3
|
|
3
|
|
3
|
https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/bacillus-anthracis-material-safety-data-sheets-msds.html
|
Biosafety level 3 practices and facilities are recommended for work with anthrax; Agriculture Canada may also require special conditions for the use or importation of this agent
|
3
|
|
3*
|
|
3
|
T, V, Z
|
3
|
Except for attenuated starins devoid of pX02 and/or pX01
|
First Schedule Part II
|
3
|
|
3
|
Vaccine available
|
Yes
|
Yes
|
No
|
Yes
|
Yes
|
bacteria
|
Mycobacterium
|
triplex
|
2
|
|
2
|
|
|
2
|
|
|
|
|
|
|
|
|
2
|
|
|
|
|
2
|
TMP
|
|
|
Yes
|
No
|
No
|
No
|
No
|
virus
|
Coronaviridae
|
Coronavirus
|
2
|
|
2
|
3
|
|
|
|
|
https://www.canada.ca/en/public-health/services/laboratory-biosafety-biosecurity/pathogen-safety-data-sheets-risk-assessment/human-coronavirus.html
|
Human Coronavirus (excluding SARS-CoV)
|
2
|
|
|
|
|
|
|
|
|
|
|
2
|
|
Yes
|
Yes
|
No
|
No
|
No
|
virus
|
Retroviridae
|
Equine infectious anemia virus
|
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
1
|
t2
|
|
|
|
2
|
PM
|
|
|
No
|
Yes
|
No
|
No
|
No
|
bacteria
|
Mycoplasma
|
mycoides
|
2
|
Restricted animal pathogen
|
|
|
|
|
|
|
|
|
|
|
|
|
2
|
t3
|
|
|
|
|
|
|
|
No
|
Yes
|
No
|
No
|
Yes
|
bacteria
|
Sphingomonas
|
paucimobilis
|
|
|
|
|
|
2
|
Pseudomonas paucimobilis
|
|
|
|
|
|
|
|
2
|
|
|
|
|
2
|
Old name: Pseudomonas paucimobilis
|
|
|
Yes
|
No
|
No
|
No
|
No
|
bacteria
|
Bacillus
|
sphaericus
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
1
|
PI PIIC
|
|
|
No
|
No
|
No
|
No
|
No
|
bacteria
|
Mycobacterium
|
wolinskyi
|
2
|
|
2
|
|
|
|
|
|
|
|
|
|
|
|
2
|
|
|
|
|
2
|
|
|
|
Yes
|
No
|
No
|
No
|
No
|
virus
|
Coronaviridae
|
Porcine epidemic diarrhoea virus
|
2
|
|
|
|
|
2
|
|
|
|
|
|
|
|
|
1
|
t2
|
|
|
|
2
|
PM
|
|
|
No
|
Yes
|
No
|
No
|
No
|
virus
|
Retroviridae
|
Feline sarcoma virus (FeSV)
|
2
|
For strains that are infectious to human cells, otherwise RG1
|
|
|
|
2
|
|
|
|
|
|
|
|
|
|
|
|
|
|
2
|
PM
|
|
|
No
|
Yes
|
No
|
No
|
No
|